FILM 1899: ANNIHILATION
TRIVIA: Due to a poorly received test screening, David Ellison, a financier at Paramount, became concerned that the film was "too intellectual" and "too complicated," and demanded changes to make it appeal to a wider audience, including making Portman's character more sympathetic and changing the ending. Producer Scott Rudin sided with Garland in his desire to not alter the film, defending the film and refusing to take notes. Rudin had final cut.
Oscar Isaac filmed this movie and Star Wars: The Last Jedi (2017) on adjacent studio lots. He had the same trailer for both films and would often film scenes for both movies on the same day.
Director Alex Garland decided not to reread the novel "Annihilation." Instead, he decided to adapt it "like a dream of the book."
During the lecture, Lena describes the cells in the video presentation as "cervical cancer" from a "31-year old patient." These are most likely HeLa cells, an immortalized cell line derived from a cervical cancer taken from Henrietta Lacks. The cells are widely used in Biomedical research, and the story of how cells from a patient biopsy were derived without her consent or knowledge is shown in The Immortal Life of Henrietta Lacks(2017). The movie is based on the book of the same name, and Lena is reading a copy of the book when she sits on the couch with Kane.